St. John’s wort, an herb well known for its antidepressant activity, has been examined for its effectiveness in treating SAD. In a preliminary trial, patients with seasonal depression were given 900 mg per day of St. John’s wort in addition to either bright light (3,000 lux for two hours) or a dim light (300 lux for two hours) placebo. Both groups had significant improvement in depressive symptoms, but there was no difference between the groups. The authors concluded that St. John’s wort was beneficial with or without bright light therapy, but a placebo effect from the herb cannot be ruled out in this study. Another preliminary study asked 301 SAD patients to report the changes in their symptoms resulting from the use of St. John’s wort at 300 mg three times daily. Significant overall improvement was reported by these patients. Some of the subjects used light therapy in addition to St. John’s wort. They reported more improvement in sleep, but overall improvement was not significantly different from those using St. John’s wort alone. Double-blind research is needed to confirm the usefulness of St. John’s wort for treating SAD.
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