An extract made from the leaves of the Ginkgo biloba tree is an approved treatment for early-stage Alzheimer’s disease in Europe. While not a cure, Ginkgo biloba extract (GBE) may improve memory and quality of life and slow progression in the early stages of the disease. In addition, four double-blind trials have shown that GBE is helpful for people in early stages of Alzheimer’s disease, as well as for those experiencing another form of dementia known as multi-infarct dementia. One trial reported no effect of GBE supplementation in the treatment of Alzheimer’s disease, vascular dementia or age-associated memory impairment. However, the results of this trial have been criticized, since analysis of the results does not separate those patients with Alzheimer’s disease or vascular dementia from those with age-associated memory impairment. A comparison of placebo-controlled trials of ginkgo for Alzheimer’s disease concluded that the herb compared favorably with two prescription drugs, donepezil and tacrine, commonly used to treat the condition. Research studies have used 120 to 240 mg of GBE, standardized to contain 6% terpene lactones and 24% flavone glycosides per day, generally divided into two or three portions. GBE may need to be taken for six to eight weeks before desired actions are noticed...
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